Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RB1 | P06400 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22953954 | 0.89 | FYN (0.57) | FYNGRIN2BDRD2DRD3DRD4 | |
| SCHEMBL14494801 | 0.81 | FYN (0.80) | FYNGRIN2BDRD2DRD3RB1 | |
| SCHEMBL4220031 | 0.77 | PDGFRB (0.46) | DRD2DRD1 | |
| SCHEMBL8462877 | 0.73 | DRD2 (0.71) | FYNDRD2DRD3DRD4DRD1 | |
| Hydrochloric Acid SCHEMBL7356162 | 0.72 | DRD2 (0.69) | FYNDRD2DRD3DRD4DRD1 | |
| Hydrochloric Acid SCHEMBL7356167 | 0.72 | DRD2 (0.69) | FYNDRD2DRD3DRD4DRD1 | |
| SCHEMBL7271830 | 0.71 | DRD2 (0.52) | FYNGRIN2BDRD2DRD3DRD4 | |
| SCHEMBL9295705 | 0.71 | DRD2 (0.59) | FYNDRD2DRD3DRD4DRD1 | |
| SCHEMBL109025 | 0.70 | ERCC1 (0.53) | FYNMAPTALDH1A1KDM4E | |
| SCHEMBL13868598 | 0.70 | ERCC1 (0.53) | FYNMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021953-A2 | DOPAMINE RECEPTOR D1 AGONISTS AND METHODS OF USE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-02-04 | — | — | WO | disclosed |