Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.43 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ARG1 | P05089 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22953958 | 0.89 | FYN (0.52) | FYNGRIN2BDRD2DRD3DRD4 | |
| SCHEMBL14494801 | 0.85 | FYN (0.80) | FYNGRIN2BDRD2DRD3 | |
| SCHEMBL13868598 | 0.81 | ERCC1 (0.53) | FYNERCC1ERCC4MAPTALDH1A1 | |
| SCHEMBL7279623 | 0.79 | ADRA1A (0.54) | GRIN2BDRD2DRD3DRD4DRD1 | |
| Bromide SCHEMBL7281334 | 0.78 | ADRA1A (0.53) | GRIN2BDRD2DRD3DRD4DRD1 | |
| SCHEMBL8346672 | 0.76 | HRH3 (0.61) | ERCC1ERCC4ALDH1A1KDM4EARG1 | |
| SCHEMBL7271830 | 0.75 | DRD2 (0.52) | FYNGRIN2BDRD2DRD3DRD4 | |
| Bromide SCHEMBL7281324 | 0.73 | GRIN2B (0.41) | GRIN2BDRD2DRD3DRD4MAPT | |
| SCHEMBL11022881 | 0.73 | FYN (0.45) | FYNGRIN2BDRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL7356162 | 0.73 | DRD2 (0.69) | FYNDRD2DRD3DRD4DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021953-A2 | DOPAMINE RECEPTOR D1 AGONISTS AND METHODS OF USE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-02-04 | — | — | WO | disclosed |