Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 7/20 | 0.33 |
| ▸ | JAK3 | P52333 | 6/20 | 0.33 |
| ▸ | JAK1 | P23458 | 5/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22954961 | 0.92 | CCNT1 (0.34) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL22954943 | 0.90 | IRAK4 (0.34) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL22954939 | 0.86 | KMT2A (0.36) | ALDH1A1MAPTKMT2A | |
| SCHEMBL22955446 | 0.85 | SLC9A1 (0.33) | ALDH1A1MAPTKCNH2 | |
| SCHEMBL22954942 | 0.83 | CNR1 (0.34) | MAPTMEN1KMT2ATSHRNPSR1 | |
| SCHEMBL22954989 | 0.82 | ALDH1A1 (0.33) | ALDH1A1KCNH2 | |
| SCHEMBL22941608 | 0.82 | JAK1 (0.36) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL24120484 | 0.81 | KDM4E (0.32) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL22954938 | 0.81 | — | — | |
| SCHEMBL22954921 | 0.80 | GPR119 (0.47) | MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018833-A1 | CYCLOHEXANEDIONES AS HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-02-04 | — | — | WO | disclosed |