SCHEMBL22955563

SCHEMBL22955563

CC#Cc1cc(C)c(C2C(=O)CC(C3CN(C(C)=O)C3)CC2=O)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22954995 0.89 HTR2A (0.33)
SCHEMBL22955446 0.88 SLC9A1 (0.33)
SCHEMBL22955125 0.87 ALDH1A1 (0.30)
SCHEMBL22955124 0.87 KDM1A (0.35) CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL22907771 0.87 CNR1 (0.31) CHRNB2CHRNB4CHRNA3CHRNA4DPP4
SCHEMBL22954948 0.86
SCHEMBL22955567 0.84 CHRNB2 (0.41) CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL22954943 0.84 IRAK4 (0.34)
SCHEMBL22955123 0.84 JAK1 (0.32)
SCHEMBL22955121 0.84 CSNK1D (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021018833-A1 CYCLOHEXANEDIONES AS HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2021-02-04 WO disclosed