Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22955948 | 0.92 | GAA (0.44) | GAARBP4EPHX2L3MBTL1EPHX1 | |
| SCHEMBL22955937 | 0.92 | CHRNB2 (0.41) | DRD2PDE4BGAARBP4L3MBTL1 | |
| SCHEMBL22954960 | 0.90 | GRM4 (0.39) | ADRA1AGRM4 | |
| SCHEMBL22992172 | 0.87 | PDE4B (0.43) | DRD2PDE4BGAARBP4EPHX2 | |
| SCHEMBL22954945 | 0.87 | MEN1 (0.44) | PDE4BGAAL3MBTL1MEN1KMT2A | |
| SCHEMBL21344243 | 0.86 | CCR8 (0.46) | DRD2PDE4BGAARBP4EPHX2 | |
| SCHEMBL24120297 | 0.84 | PDE4B (0.38) | DRD2PDE4BGAARBP4L3MBTL1 | |
| SCHEMBL22955565 | 0.83 | CHRNB2 (0.47) | GAARBP4EPHX2L3MBTL1MEN1 | |
| SCHEMBL22954946 | 0.83 | QDPR (0.36) | PDE4BSLC9A1 | |
| SCHEMBL22954994 | 0.82 | PDE2A (0.45) | GAAEPHX2L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018833-A1 | CYCLOHEXANEDIONES AS HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-02-04 | — | — | WO | disclosed |