Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22992066 | 0.89 | GRM4 (0.39) | PDE4BADRA1DADRA1AADRA1BGAA | |
| SCHEMBL21344243 | 0.88 | CCR8 (0.46) | PDE4BMEN1KMT2AL3MBTL1ADRA1D | |
| SCHEMBL22955944 | 0.87 | DRD2 (0.40) | PDE4BMEN1KMT2AL3MBTL1ADRA1D | |
| SCHEMBL22992177 | 0.87 | ALDH1A1 (0.43) | PDE4BMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL24120297 | 0.86 | PDE4B (0.38) | PDE4BMEN1KMT2AL3MBTL1ADRA1D | |
| SCHEMBL22955937 | 0.85 | CHRNB2 (0.41) | PDE4BMEN1KMT2AL3MBTL1ADRA1D | |
| SCHEMBL21344636 | 0.80 | L3MBTL1 (0.44) | L3MBTL1GAAEPHX2CCR8KCNH2 | |
| SCHEMBL22908539 | 0.79 | CCR8 (0.47) | PDE4BMEN1KMT2AL3MBTL1ADRA1D | |
| SCHEMBL22955948 | 0.79 | GAA (0.44) | L3MBTL1GAAEPHX2RBP4PDE2A | |
| SCHEMBL24120410 | 0.78 | L3MBTL1 (0.40) | PDE4BL3MBTL1GAAEPHX2CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, GLRX3 | PDE4B 562/4885MEN1 3738/4885KMT2A 656/4885 |
| US-12043599-B2 | Herbicidal compounds | DDT, CBR3, GLRX3 | PDE4B 562/4885MEN1 3738/4885KMT2A 656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.