SCHEMBL22956804

SCHEMBL22956804

C[Si]1(C)c2ccccc2-c2ccccc2-c2ccc(Cl)cc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.46
RORA P35398 1/20 0.41
RORC P51449 1/20 0.41
GPR3 P46089 1/20 0.40
CYP2A6 P11509 1/20 0.34
KDM4E B2RXH2 2/20 0.34
NPC1 O15118 2/20 0.34
ALDH1A1 P00352 2/20 0.34
RAB9A P51151 2/20 0.34
PDK2 Q15119 2/20 0.34
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
HSD11B1 P28845 3/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPK1 P28482 1/20 0.33
ITGA1 P56199 1/20 0.31
AKR1A1 P14550 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17068902 0.98 RORA (0.42) S100A4RORARORCGPR3CYP2A6
SCHEMBL31267454 0.98 RORA (0.42) S100A4RORARORCGPR3CYP2A6
SCHEMBL20794264 0.96 S100A4 (0.48) S100A4RORARORCGPR3CYP2A6
SCHEMBL24123203 0.86 RORC (0.50) S100A4RORARORCGPR3CYP2A6
SCHEMBL30701881 0.86 RORC (0.50) S100A4RORARORCGPR3CYP2A6
SCHEMBL22947541 0.84 CYP1A2 (0.42) S100A4RORARORCGPR3KDM4E
SCHEMBL27394818 0.83 RORA (0.34) S100A4RORARORCGPR3
SCHEMBL27394633 0.82 CYP2A6 (0.43) S100A4RORARORCGPR3CYP2A6
SCHEMBL27394478 0.81 PDK2 (0.43) RORARORCPDK2
SCHEMBL22884223 0.80 CYP1A2 (0.47) KDM4ENPC1ALDH1A1RAB9APDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11706973-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-18 US disclosed
US-11706973-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-18 US disclosed
US-20210104673-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2021-04-08 US disclosed
US-10916708-B2 Condensed cyclic compound and organic light emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10916708-B2 Condensed cyclic compound and organic light emitting device including the same C1S, C9, CCNT1 S100A4 2890/4885RORA 1928/4885RORC 2318/4885
US-11706973-B2 Condensed cyclic compound and organic light-emitting device including the same C1S, CCNT1, C9 S100A4 2739/4885RORA 2029/4885RORC 2466/4885
US-20210104673-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME C1S, CCNT1, C9 S100A4 2739/4885RORA 2029/4885RORC 2466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.