Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24018774 | 1.00 | KCNK3 (0.44) | KCNK3KCNK9CA1CA2ACHE | |
| SCHEMBL22957654 | 0.87 | KCNK3 (0.42) | KCNK3KCNK9CA1CA2ACHE | |
| SCHEMBL24018814 | 0.84 | SLC6A4 (0.53) | KCNK3KCNK9CA1CA2ACHE | |
| SCHEMBL22957675 | 0.82 | KCNK3 (0.39) | KCNK3KCNK9CA1CA2ACHE | |
| SCHEMBL807278 | 0.80 | KCNK3 (0.52) | KCNK3KCNK9CA1CA2SLC6A4 | |
| SCHEMBL8593107 | 0.80 | CA1 (0.56) | KCNK3KCNK9CA1CA2ACHE | |
| SCHEMBL21882592 | 0.77 | KCNK3 (0.43) | KCNK3KCNK9SLC6A4EGFRPPARG | |
| SCHEMBL24779813 | 0.77 | KCNK3 (0.43) | KCNK3KCNK9SLC6A4HPGDSMN1; SMN2 | |
| SCHEMBL10192275 | 0.77 | KCNK3 (0.43) | KCNK3KCNK9SLC6A4PPARGPPARD | |
| SCHEMBL5924730 | 0.77 | KCNK3 (0.43) | KCNK3KCNK9SLC6A4PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913738-B2 | Aminotriazolopyridines as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913738-B2 | Aminotriazolopyridines as kinase inhibitors | RIPK1, RIPK3, RIPK4 | KCNK3 398/4885KCNK9 359/4885CA1 4488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.