Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.46 |
| ▸ | HTR2A | P28223 | 5/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130662 | 0.84 | MCL1 (0.53) | MCL1ALDH1A1PKMSLC6A4HTR2A | |
| SCHEMBL22957643 | 0.84 | HTT (0.48) | MCL1ALDH1A1PKMKCNH2CCR8 | |
| SCHEMBL22957679 | 0.84 | ATM (0.42) | ALDH1A1KCNH2CCR8POLBGAA | |
| SCHEMBL12852529 | 0.77 | MCL1 (0.53) | MCL1ALDH1A1PKMSLC6A4HTR2A | |
| SCHEMBL8089375 | 0.77 | KCNH2 (0.39) | ALDH1A1SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL8095035 | 0.77 | KCNH2 (0.37) | ALDH1A1SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL2164875 | 0.75 | TSHR (0.39) | ALDH1A1KCNH2CCR8POLBGAA | |
| SCHEMBL30881973 | 0.75 | TSHR (0.39) | ALDH1A1KCNH2CCR8POLBGAA | |
| SCHEMBL22957694 | 0.75 | MCL1 (0.58) | MCL1ALDH1A1PKMSLC6A4HTR2A | |
| SCHEMBL6151984 | 0.73 | SLC6A4 (0.66) | SLC6A4HTR2ASLC6A2SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3580220-B1 | AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-17 | — | — | EP | disclosed |
| US-10913738-B2 | Aminotriazolopyridines as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913738-B2 | Aminotriazolopyridines as kinase inhibitors | RIPK1, RIPK3, RIPK4 | MCL1 1442/4885ALDH1A1 4194/4885PKM 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.