SCHEMBL2164875

SCHEMBL2164875

FC(F)C(F)(F)Oc1ccccc1OC(F)(F)C(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 3/20 0.39
POLB P06746 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
KDM4E B2RXH2 4/20 0.35
LMNA P02545 4/20 0.35
MAPT P10636 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
HSP90AA1 P07900 1/20 0.35
GAA P10253 1/20 0.35
NCOA1 Q15788 1/20 0.35
NCOA3 Q9Y6Q9 1/20 0.35
CCR8 P51685 1/20 0.35
KCNH2 Q12809 1/20 0.35
HTT P42858 2/20 0.34
ALOX12 P18054 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30881973 1.00 TSHR (0.39) TSHRMAPK1ALDH1A1POLBTDP1
SCHEMBL6443536 0.89 CA1 (0.54) TSHRMAPK1ALDH1A1TDP1L3MBTL1
SCHEMBL7524628 0.86 TSHR (0.39) TSHRMAPK1ALDH1A1POLBTDP1
SCHEMBL14388549 0.86 TSHR (0.36) TSHRMAPK1ALDH1A1POLBTDP1
SCHEMBL11113862 0.84 TSHR (0.35) TSHRMAPK1ALDH1A1POLBTDP1
SCHEMBL4790420 0.84 TSHR (0.45) TSHRMAPK1ALDH1A1POLBTDP1
SCHEMBL418646 0.84 ALDH1A1 (0.45) TSHRMAPK1ALDH1A1TDP1L3MBTL1
SCHEMBL1619385 0.84 MEN1 (0.36) TSHRMAPK1ALDH1A1POLBTDP1
SCHEMBL10979488 0.84 KMT2A (0.40) TSHRMAPK1ALDH1A1MEN1KMT2A
SCHEMBL6296270 0.84 TSHR (0.39) TSHRMAPK1ALDH1A1POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3900102-B1 METHOD FOR EXCHANGING HEAT WITH A BATTERY USING FLUORINATED COMPOUNDS HAVING A LOW GWP SOLVAY SPECIALTY POLYMERS IT (IT) 2023-04-05 EP claimed
US-20220025240-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICES USING A HEAT TRANSFER FLUID COMPRISING FLUORINATED COMPOUNDS HAVING A LOW GWP Syensqo Specialty Polymers Italy S.p.A. (IT) 2022-01-27 US claimed
US-20220021051-A1 METHOD FOR EXCHANGING HEAT WITH A BATTERY USING FLUORINATED COMPOUNDS HAVING A LOW GWP Syensqo Specialty Polymers Italy S.p.A. (IT) 2022-01-20 US claimed
US-12036563-B2 Process for separating mixtures of solids SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2024-07-16 US disclosed
EP-3900102-B1 METHOD FOR EXCHANGING HEAT WITH A BATTERY USING FLUORINATED COMPOUNDS HAVING A LOW GWP SOLVAY SPECIALTY POLYMERS IT (IT) 2023-04-05 EP disclosed
EP-3917999-B1 PROCESS FOR SEPARATING MIXTURES OF SOLIDS SOLVAY SPECIALTY POLYMERS USA (US) 2023-03-08 EP disclosed
US-20220118464-A1 PROCESS FOR SEPARATING MIXTURES OF SOLIDS SOLVAY SPECIALITY POLYMERS USA, LLC 2022-04-21 US disclosed
US-20220025240-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICES USING A HEAT TRANSFER FLUID COMPRISING FLUORINATED COMPOUNDS HAVING A LOW GWP Syensqo Specialty Polymers Italy S.p.A. (IT) 2022-01-27 US disclosed
US-20220021051-A1 METHOD FOR EXCHANGING HEAT WITH A BATTERY USING FLUORINATED COMPOUNDS HAVING A LOW GWP Syensqo Specialty Polymers Italy S.p.A. (IT) 2022-01-20 US disclosed
EP-3900102-A1 METHOD FOR EXCHANGING HEAT WITH A BATTERY USING FLUORINATED COMPOUNDS HAVING A LOW GWP Solvay Specialty Polymers Italy S.p.A. (IT) 2021-10-27 EP disclosed
WO-2020127666-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICES USING A HEAT TRANSFER FLUID COMPRISING FLUORINATED COMPOUNDS HAVING A LOW GWP SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2020-06-25 WO disclosed
US-20110180761-A1 METHOD FOR THE APPLICATION OF ACTIVE MATERIALS ONTO A SURFACES AND DEVICES MADE WITH SUCH METHODS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-28 US disclosed
US-20110180761-A1 METHOD FOR THE APPLICATION OF ACTIVE MATERIALS ONTO A SURFACES AND DEVICES MADE WITH SUCH METHODS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-28 US disclosed
US-7686978-B2 Method for the application of active materials onto active surfaces and devices made with such methods E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-30 US disclosed
US-7686978-B2 Method for the application of active materials onto active surfaces and devices made with such methods E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-30 US disclosed
US-7531700-B2 Fluorinated arylethers and methods for use thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-12 US disclosed
US-20050269550-A1 Method for the application of active materials onto active surfaces and devices made with such methods PETROV VIACHESLAV A 2005-12-08 US disclosed
US-20050062021-A1 Method for the application of active materials onto active surfaces and devices made with such methods LG CHEM, LTD. (KR) 2005-03-24 US disclosed
US-5162468-A Polymers containing perfluorocyclobutane rings THE DOW CHEMICAL COMPANY (US) 1992-11-10 US disclosed
US-5023380-A Monomer for thermoplastic resin THE DOW CHEMICAL COMPANY (US) 1991-06-11 US disclosed