Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.32 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22957696 | 0.88 | KDM4E (0.37) | RIPK1TRPV3KDM4EHTTTDP1 | |
| SCHEMBL22957697 | 0.81 | RIPK1 (0.41) | MEN1KMT2ARIPK1KDM4EALDH1A1 | |
| SCHEMBL24180186 | 0.81 | ALOX5AP (0.35) | MEN1CYP1A2CYP2C19KMT2ARIPK1 | |
| SCHEMBL22957867 | 0.80 | MCL1 (0.43) | MEN1KMT2ARIPK1KDM4ETDP1 | |
| SCHEMBL22957665 | 0.80 | RIPK1 (0.37) | RIPK1KDM4EKDM1AMAOAPKM | |
| SCHEMBL24018799 | 0.77 | MAPT (0.39) | MEN1CYP1A2KMT2ARIPK1KDM4E | |
| SCHEMBL22957708 | 0.76 | NTRK1 (0.42) | MEN1CYP1A2CYP2C19KMT2ARIPK1 | |
| SCHEMBL25921571 | 0.74 | TDP1 (0.38) | MEN1CYP2C19KMT2AKDM4EHTT | |
| SCHEMBL22389465 | 0.73 | L3MBTL1 (0.36) | MEN1KMT2ARIPK1KDM4ETDP1 | |
| SCHEMBL20414387 | 0.73 | HTT (0.57) | MEN1KMT2AKDM4EHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913738-B2 | Aminotriazolopyridines as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913738-B2 | Aminotriazolopyridines as kinase inhibitors | RIPK1, RIPK3, RIPK4 | MEN1 3915/4885CYP1A2 2727/4885CYP2C19 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.