SCHEMBL22958720

SCHEMBL22958720

c1ccc(-c2ccc3c4ccccc4n(-c4cc5c6c(c4)Oc4cc(-c7ccccc7-c7ccccc7)ccc4N6c4ccc(-c6ccccc6-c6ccccc6)cc4O5)c3c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
MAPK14 Q16539 1/20 0.32
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25636733 0.92 L3MBTL1 (0.40) KDM4EATML3MBTL1EDNRBEDNRA
SCHEMBL22958717 0.92 CA12 (0.34) KDM4EATML3MBTL1EDNRBEDNRA
SCHEMBL22958752 0.88 EDNRB (0.36) KDM4EATML3MBTL1EDNRBEDNRA
SCHEMBL22958671 0.87 L3MBTL1 (0.38) KDM4EATML3MBTL1EDNRBEDNRA
SCHEMBL20208610 0.87 KDM4E (0.38) KDM4EATML3MBTL1MAPK14
SCHEMBL22958677 0.86 ALOX5 (0.40)
SCHEMBL22958791 0.86 KDM4E (0.37) KDM4EATML3MBTL1EDNRBEDNRA
SCHEMBL22958735 0.84 EDNRB (0.37) KDM4EATML3MBTL1EDNRBEDNRA
SCHEMBL22958727 0.83 L3MBTL1 (0.42) KDM4EATML3MBTL1EDNRBEDNRA
SCHEMBL20208602 0.83 L3MBTL1 (0.41) KDM4EATML3MBTL1EDNRBEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210043852-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-02-11 US disclosed