Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2182127 | 0.93 | CRHR1 (0.61) | CRHR1CRHR2KMT2APOLBHSD17B10 | |
| SCHEMBL2180543 | 0.89 | CRHR1 (0.54) | CRHR1CRHR2KMT2APOLBHSD17B10 | |
| SCHEMBL29430976 | 0.87 | CRHR1 (0.57) | CRHR1CRHR2KMT2APOLBHSD17B10 | |
| SCHEMBL29256009 | 0.86 | CRHR1 (0.54) | CRHR1CRHR2KMT2APOLBHSD17B10 | |
| SCHEMBL2931339 | 0.83 | CRHR1 (0.52) | CRHR1CRHR2KMT2APOLBHSD17B10 | |
| SCHEMBL25490371 | 0.83 | CRHR1 (0.56) | CRHR1CRHR2KMT2APOLBHSD17B10 | |
| SCHEMBL25490375 | 0.83 | CRHR1 (0.49) | CRHR1CRHR2KMT2APOLBHSD17B10 | |
| SCHEMBL2928067 | 0.81 | CRHR1 (0.50) | CRHR1CRHR2KMT2APOLBHSD17B10 | |
| SCHEMBL27051835 | 0.81 | CRHR1 (0.50) | CRHR1CRHR2KMT2APOLBHSD17B10 | |
| SCHEMBL2496095 | 0.81 | CRHR1 (0.49) | CRHR1CRHR2KMT2APOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210038604-A1 | METHODS FOR TREATING TESTICULAR AND OVARIAN ADRENAL REST TUMORS | AVENUE CAPITAL MANAGEMENT II, L.P. | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210038604-A1 | METHODS FOR TREATING TESTICULAR AND OVARIAN ADRENAL REST TUMORS | NR5A1, SHBG, CYP17A1 | CRHR1 50/4885CRHR2 61/4885KMT2A 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.