SCHEMBL22960418

SCHEMBL22960418

c1ccc(-c2cc(-c3ccccc3)cc(-c3cccc(-n4c5ccccc5c5c6ccccc6c6c7ccccc7sc6c54)c3)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
RXFP1 Q9HBX9 1/20 0.36
TP53 P04637 2/20 0.34
ATM Q13315 2/20 0.33
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TNKS O95271 2/20 0.32
TNKS2 Q9H2K2 2/20 0.32
HSD17B10 Q99714 1/20 0.31
FAAH O00519 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HSP90AA1 P07900 1/20 0.31
PKM P14618 1/20 0.31
HTT P42858 1/20 0.31
MGLL Q99685 1/20 0.31
LIMK1 P53667 1/20 0.30
KMT2A Q03164 1/20 0.30
IL1R1 P14778 1/20 0.30
HTR1A P08908 1/20 0.30
HTR7 P34969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22960405 0.99 MAPT (0.37) MAPTRXFP1TP53ATMKDM4E
SCHEMBL17990808 0.94 TNKS (0.34) MAPTRXFP1ATMKDM4EL3MBTL1
SCHEMBL19985938 0.93 MAPT (0.36) MAPTRXFP1TP53ATMKDM4E
SCHEMBL17990884 0.92 MAPT (0.35) MAPTRXFP1TP53ATMKDM4E
SCHEMBL17990901 0.92 MAPT (0.35) MAPTRXFP1TP53ATMKDM4E
SCHEMBL19985937 0.92 MAPT (0.37) MAPTRXFP1TP53ATMKDM4E
SCHEMBL23960976 0.92 MAPT (0.37) MAPTRXFP1TP53ATMKDM4E
SCHEMBL19985920 0.91 MAPT (0.36) MAPTRXFP1TP53ATMKDM4E
SCHEMBL17246617 0.90 L3MBTL1 (0.35) MAPTRXFP1TP53ATMKDM4E
SCHEMBL19039774 0.90 MAPT (0.33) MAPTRXFP1TP53ATMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-04 US disclosed
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-04 US disclosed
US-20210043848-A1 COMPOSITION MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 MAPT 940/4885RXFP1 4860/4885TP53 2287/4885
US-20210043848-A1 COMPOSITION MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LIMS1, TERT, TELO2 MAPT 507/4885RXFP1 4845/4885TP53 1416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.