Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSGALNACT1 | Q8TDX6 | 9/20 | 0.63 |
| ▸ | KDR | P35968 | 6/20 | 0.58 |
| ▸ | FLT3 | P36888 | 4/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.47 |
| ▸ | FLT1 | P17948 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | TEK | Q02763 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.47 |
| ▸ | RET | P07949 | 2/20 | 0.47 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2296399 | 1.00 | CSGALNACT1 (0.63) | CSGALNACT1KDRFLT3PDGFRBKIT | |
| SCHEMBL2293805 | 0.92 | CSGALNACT1 (0.70) | CSGALNACT1KDRFLT3PDGFRBKIT | |
| SCHEMBL2293801 | 0.92 | CSGALNACT1 (0.70) | CSGALNACT1KDRFLT3PDGFRBKIT | |
| SCHEMBL2296315 | 0.86 | CSGALNACT1 (0.59) | CSGALNACT1MEN1KMT2AMAPT | |
| SCHEMBL2296314 | 0.86 | CSGALNACT1 (0.59) | CSGALNACT1MEN1KMT2AMAPT | |
| SCHEMBL2296660 | 0.83 | CSGALNACT1 (0.84) | CSGALNACT1KDRDGAT1 | |
| SCHEMBL2301030 | 0.83 | RAB9A (0.52) | CSGALNACT1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL2301026 | 0.83 | RAB9A (0.52) | CSGALNACT1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL2296712 | 0.81 | CSGALNACT1 (0.62) | CSGALNACT1KDRFLT3PDGFRBSMN1; SMN2 | |
| SCHEMBL2296714 | 0.81 | CSGALNACT1 (0.62) | CSGALNACT1KDRFLT3PDGFRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835428-B2 | Diacylglycerol acyltransferase inhibitors | Piramal Enterprises Limited (IN) | 2014-09-16 | — | — | US | disclosed |
| US-20110196002-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED. | 2011-08-11 | — | — | US | disclosed |
| WO-2010023609-A1 | OXAZOLE, OXADIAZOLE AND THIAZOLE DERIVATIVES AS DIACYLGLYCEROL ACYLTRANFERASE INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110196002-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | DGAT1, DGAT2, DLAT | CSGALNACT1 455/4885KDR 4609/4885FLT3 3416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.