Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | APAF1 | O14727 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | TNF | P01375 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | FABP3 | P05413 | 1/20 | 0.54 |
| ▸ | FABP4 | P15090 | 1/20 | 0.54 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516010 | 0.91 | LMNA (0.62) | LMNAKDM4EKMT2AL3MBTL1APAF1 | |
| SCHEMBL22965215 | 0.90 | LMNA (0.60) | LMNAKDM4EKMT2AL3MBTL1APAF1 | |
| SCHEMBL540852 | 0.88 | LMNA (0.59) | LMNAKDM4EKMT2AL3MBTL1APAF1 | |
| SCHEMBL3587930 | 0.84 | KDM4E (0.69) | LMNAKDM4EKMT2AAPAF1SMN1; SMN2 | |
| SCHEMBL14616345 | 0.84 | ALDH1A1 (0.58) | LMNAKDM4EAPAF1SMN1; SMN2TNF | |
| SCHEMBL9694037 | 0.83 | KDM4E (0.73) | LMNAKDM4EKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL6446137 | 0.83 | LMNA (0.69) | LMNAAPAF1SMN1; SMN2RAB9ATNF | |
| SCHEMBL22965266 | 0.82 | KDM4E (0.59) | LMNAKDM4EKMT2AAPAF1SMN1; SMN2 | |
| SCHEMBL14575429 | 0.82 | TSHR (0.62) | LMNAKDM4EAPAF1SMN1; SMN2HTT | |
| SCHEMBL22639681 | 0.82 | KMT2A (0.74) | LMNAKDM4EKMT2AL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023796-A1 | COMPOSITIONS FOR TRANSFECTING A NUCLEIC ACID MOLECULE INTO A CELL COMPRISING HETEROCYCLIC COMPOUNDS GRAFTED TO A CATIONIC POLYMER, AND THEIR APPLICATIONS | POLYPLUS TRANSFECTION (FR) | 2021-02-11 | — | — | WO | disclosed |