Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | FABP4 | P15090 | 2/20 | 0.57 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.57 |
| ▸ | APAF1 | O14727 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL540852 | 0.99 | LMNA (0.59) | LMNAHTTTP53FABP4FABP5 | |
| SCHEMBL28516010 | 0.96 | LMNA (0.62) | LMNAHTTTP53FABP4FABP5 | |
| SCHEMBL22965263 | 0.90 | LMNA (0.65) | LMNAHTTTP53FABP4FABP5 | |
| SCHEMBL2330274 | 0.85 | LMNA (0.69) | LMNAHTTTP53ALDH1A1P2RX7 | |
| SCHEMBL22965212 | 0.84 | PTGDR2 (0.59) | LMNAHTTTP53APAF1ALDH1A1 | |
| SCHEMBL540948 | 0.84 | FAAH (0.57) | LMNAHTTTP53APAF1ALDH1A1 | |
| SCHEMBL28890678 | 0.82 | KDM4E (0.56) | LMNAHTTTP53FABP4FABP5 | |
| SCHEMBL10389744 | 0.82 | LMNA (0.62) | LMNAHTTTP53APAF1ALDH1A1 | |
| SCHEMBL5813721 | 0.81 | FABP4 (0.55) | LMNAHTTTP53FABP4FABP5 | |
| SCHEMBL3587930 | 0.80 | KDM4E (0.69) | LMNAHTTAPAF1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023796-A1 | COMPOSITIONS FOR TRANSFECTING A NUCLEIC ACID MOLECULE INTO A CELL COMPRISING HETEROCYCLIC COMPOUNDS GRAFTED TO A CATIONIC POLYMER, AND THEIR APPLICATIONS | POLYPLUS TRANSFECTION (FR) | 2021-02-11 | — | — | WO | disclosed |