Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2297591 | 1.00 | ADRA2A (0.36) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| SCHEMBL852082 | 1.00 | ADRA2A (0.36) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| SCHEMBL5731186 | 0.85 | HTT (0.41) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| SCHEMBL16655538 | 0.82 | HTT (0.39) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| SCHEMBL5729433 | 0.81 | MAP3K14 (0.31) | — | |
| SCHEMBL5730876 | 0.81 | HTT (0.38) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| SCHEMBL12361954 | 0.81 | ALDH1A1 (0.36) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| SCHEMBL417702 | 0.81 | POLB (0.37) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| SCHEMBL17272433 | 0.81 | ADRA2A (0.33) | ADRA2AADRA1AHTTHTR1ADRD1 | |
| SCHEMBL1141455 | 0.81 | ALDH1A1 (0.34) | ADRA2AADRA1AHTTHTR1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994345-B2 | Process for the purification of thiophenes | H. C. STARCK GMBH (DE) | 2011-08-09 | — | — | US | disclosed |
| US-20090318710-A1 | PROCESS FOR THE PURIFICATION OF THIOPHENES | H. C. STARCK GMBH (DE) | 2009-12-24 | — | — | US | disclosed |
| US-20050065352-A1 | Process for the purification of thiophenes | H.C. STARCK GMBH (DE) | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318710-A1 | PROCESS FOR THE PURIFICATION OF THIOPHENES | C1S, THOP1, GTF2E2 | ADRA2A 4182/4885ADRA1A 3275/4885HTT 1747/4885 |
| US-20050065352-A1 | Process for the purification of thiophenes | C1S, THOP1, GTF2E2 | ADRA2A 4182/4885ADRA1A 3275/4885HTT 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.