Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26351862 | 0.98 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL26351863 | 0.98 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL26351869 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1KMT2AGAASLC6A3 | |
| SCHEMBL27323531 | 0.86 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL21671917 | 0.82 | ADORA2A (0.39) | SMN1; SMN2ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL26351827 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL26351828 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL9738718 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL31239605 | 0.76 | SLC6A3 (0.35) | ALDH1A1KMT2AGAAMEN1SLC6A3 | |
| SCHEMBL13865731 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1KMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040118-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040118-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | IL2, IL5, TSLP | SMN1; SMN2 4120/4885ALDH1A1 658/4885KMT2A 4130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.