Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18757473 | 0.73 | CYP3A4 (0.41) | ALDH1A1TSHR | |
| SCHEMBL7187600 | 0.72 | ALDH1A1 (0.63) | ALDH1A1TSHR | |
| SCHEMBL18758026 | 0.71 | CYP3A4 (0.44) | ALDH1A1TSHR | |
| SCHEMBL11527121 | 0.70 | ALDH1A1 (0.60) | ALDH1A1TSHR | |
| SCHEMBL15371094 | 0.69 | HPGD (0.41) | ALDH1A1TSHR | |
| SCHEMBL33318 | 0.68 | — | — | |
| SCHEMBL22163154 | 0.67 | NOS2 (0.44) | — | |
| SCHEMBL21611339 | 0.65 | ALDH1A1 (0.92) | ALDH1A1TSHR | |
| Bromide SCHEMBL22747715 | 0.65 | ALDH1A1 (0.92) | ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL2862643 | 0.65 | ALDH1A1 (0.92) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026099-A1 | KIF18A INHIBITORS | AMGEN INC. (US) | 2021-02-11 | — | — | WO | disclosed |