Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.34 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATF4 | P18848 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22967215 | 1.00 | ROCK2 (0.41) | ROCK2ROCK1QPCTCHEK2SUV39H1 | |
| SCHEMBL22967056 | 0.91 | ADORA2A (0.39) | ROCK2ROCK1LMNAATF4ADORA2A | |
| SCHEMBL22967060 | 0.91 | ADORA2A (0.41) | LMNAADORA2AADORA2BPDE3BPDE3A | |
| SCHEMBL22967264 | 0.88 | LMNA (0.33) | ROCK2ROCK1LMNAATF4ADORA2A | |
| SCHEMBL21217861 | 0.81 | ROCK2 (0.61) | ROCK2ROCK1RAB9A | |
| SCHEMBL22967219 | 0.81 | ROCK2 (0.61) | ROCK2ROCK1RAB9A | |
| SCHEMBL22966751 | 0.81 | ROCK2 (0.61) | ROCK2ROCK1RAB9A | |
| SCHEMBL22967237 | 0.79 | CYP1A2 (0.43) | ROCK2ADORA2AADORA2BHPGD | |
| SCHEMBL22967263 | 0.79 | MAPT (0.32) | LMNAADORA2AADORA2BRAB9A | |
| SCHEMBL22967055 | 0.79 | CDK4 (0.45) | QPCTLMNAHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210038606-A1 | Modulators of Rho-associated Protein Kinase | REDX PHARMA LIMITED (GB) | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210038606-A1 | Modulators of Rho-associated Protein Kinase | ROCK2, ROCK1, RHOA | ROCK2 1/4885ROCK1 2/4885QPCT 2782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.