Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATF4 | P18848 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.32 |
| ▸ | SLC2A3 | P11169 | 3/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22967060 | 0.91 | ADORA2A (0.41) | LMNAKMT2AMEN1POLBADORA2A | |
| SCHEMBL22967056 | 0.91 | ADORA2A (0.39) | LMNAATF4KMT2AMEN1ADORA2A | |
| SCHEMBL22967259 | 0.88 | ROCK2 (0.41) | LMNAATF4ADORA2AADORA2BHPGD | |
| SCHEMBL22967215 | 0.88 | ROCK2 (0.41) | LMNAATF4ADORA2AADORA2BHPGD | |
| SCHEMBL22967263 | 0.84 | MAPT (0.32) | LMNAKMT2APOLBMAPTADORA2A | |
| SCHEMBL22967237 | 0.81 | CYP1A2 (0.43) | MAPTADORA2AADORA2BHPGDROCK2 | |
| SCHEMBL22966753 | 0.80 | ROCK2 (0.50) | KMT2AMEN1POLBSLC2A1SLC2A3 | |
| SCHEMBL22967055 | 0.79 | CDK4 (0.45) | LMNAKMT2AMEN1POLBMAPT | |
| SCHEMBL22967260 | 0.79 | ADORA2B (0.35) | LMNAADORA2AADORA2B | |
| SCHEMBL24094162 | 0.79 | CTDSP1 (0.39) | LMNAKMT2AMEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210038606-A1 | Modulators of Rho-associated Protein Kinase | REDX PHARMA LIMITED (GB) | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210038606-A1 | Modulators of Rho-associated Protein Kinase | ROCK2, ROCK1, RHOA | LMNA 3657/4885ATF4 1161/4885KMT2A 2192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.