Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20314462 | 0.74 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL22967661 | 0.72 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL18086916 | 0.72 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL22967647 | 0.71 | SLC6A2 (0.30) | SLC6A4 | |
| SCHEMBL22970032 | 0.71 | — | — | |
| SCHEMBL19958990 | 0.71 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL12526964 | 0.70 | — | — | |
| SCHEMBL6138064 | 0.68 | NLRP3 (0.34) | ALDH1A1SLC6A4 | |
| SCHEMBL19015222 | 0.67 | — | — | |
| SCHEMBL16089702 | 0.67 | ALDH1A1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040089-A1 | KRAS MUTANT PROTEIN INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040089-A1 | KRAS MUTANT PROTEIN INHIBITORS | KRAS, NRAS, APC | ALDH1A1 3926/4885SLC6A4 4870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.