SCHEMBL2296932

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2300889	0.93	NAMPT (0.37)	SPRNAMPTMGLL
	SCHEMBL2303903	0.86	PKM (0.45)	GAAHPGDKMT2A
	SCHEMBL2299298	0.86	NAMPT (0.41)	NAMPTMBTD1L3MBTL3ALDH1A1MGLL
	SCHEMBL2301150	0.86	NAMPT (0.41)	NAMPTMBTD1L3MBTL3ALDH1A1MGLL
	SCHEMBL2296894	0.86	NAMPT (0.41)	NAMPTMBTD1L3MBTL3ALDH1A1MGLL
	SCHEMBL2296908	0.85	CHKA (0.41)	ALDH1A1GAAHPGDPDE5APDE4A
	SCHEMBL2302192	0.85	CHKA (0.41)	ALDH1A1GAAHPGDPDE5APDE4A
	SCHEMBL2021298	0.85	CHKA (0.41)	ALDH1A1GAAHPGDPDE5APDE4A
	Hydrochloric Acid SCHEMBL2300289	0.84	HTT (0.41)	ALDH1A1GAAHPGDPDE5APDE4A
	Hydrochloric Acid SCHEMBL2300283	0.84	HTT (0.41)	ALDH1A1GAAHPGDPDE5APDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.