SCHEMBL22969362

SCHEMBL22969362

c1ccc(-c2c3ccccc3c(-c3cccc(-c4ccc5c6c(cccc46)Sc4ccccc4-5)c3)c3ccccc23)cc1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.33
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
ALOX5 P09917 1/20 0.31
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
PTGER1 P34995 1/20 0.30
PTGER4 P35408 1/20 0.30
PTGER3 P43115 1/20 0.30
PTGER2 P43116 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22969187 0.99 ACHE (0.32) ACHEPDCD1CD274ALOX5
SCHEMBL22969343 0.91 PDCD1 (0.36) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL22969354 0.90 PTGER1 (0.32) PDCD1CD274ALOX5PTGER1PTGER4
SCHEMBL16558478 0.90 ACHE (0.33) ACHEPDCD1CD274ALOX5CRHBP
SCHEMBL22969179 0.90 PDCD1 (0.35) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL22969353 0.90 ACHE (0.35) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL22969349 0.89 MCL1 (0.34)
SCHEMBL22969178 0.89 PTGER1 (0.31) PTGER1PTGER4PTGER3PTGER2
SCHEMBL22969186 0.88 ACHE (0.34) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL22969342 0.87 ACHE (0.33) ACHEPDCD1CD274CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021025162-A1 NOVEL COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME, AND ELECTRONIC APPLIANCE 出光興産株式会社 2021-02-11 WO disclosed
WO-2021025163-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE USING SAME 出光興産株式会社 2021-02-11 WO disclosed