SCHEMBL16558478

SCHEMBL16558478

c1ccc(-c2c3cccc(-c4ccc5c6c(cccc46)Sc4ccccc4-5)c3cc3c(-c4ccc5c6c(cccc46)Sc4ccccc4-5)cccc23)cc1

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.33
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
ALOX5 P09917 1/20 0.31
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
TYMS P04818 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
CASP1 P29466 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22969347 0.91 CRHBP (0.34) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL22969353 0.91 ACHE (0.35) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL22969362 0.90 ACHE (0.33) ACHEPDCD1CD274ALOX5CRHBP
SCHEMBL22969194 0.90 CRHBP (0.33) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL22969343 0.90 PDCD1 (0.36) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL22969186 0.90 ACHE (0.34) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL22969187 0.89 ACHE (0.32) ACHEPDCD1CD274ALOX5
SCHEMBL22969179 0.88 PDCD1 (0.35) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL22969342 0.88 ACHE (0.33) ACHEPDCD1CD274CRHBPCRHR2
SCHEMBL22969193 0.87 ACHE (0.33) ACHEPDCD1CD274CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9601700-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-21 US disclosed
US-9601700-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-21 US disclosed
US-20150069344-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-03-12 US disclosed
US-20150069344-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-03-12 US disclosed