Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | IL2 | P60568 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.31 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | VHL | P40337 | 1/20 | 0.30 |
| ▸ | ELOC | Q15369 | 1/20 | 0.30 |
| ▸ | ELOB | Q15370 | 1/20 | 0.30 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.30 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23180460 | 0.95 | TTR (0.37) | TTRIL2KLKB1FOLH1OPRK1 | |
| SCHEMBL24176337 | 0.94 | TTR (0.37) | TTRIL2KLKB1FOLH1OPRK1 | |
| SCHEMBL20016562 | 0.93 | TTR (0.45) | TTRIL2KLKB1FOLH1OPRK1 | |
| SCHEMBL12342493 | 0.89 | OPRK1 (0.40) | TTRIL2KLKB1FOLH1OPRK1 | |
| SCHEMBL14129393 | 0.89 | OPRK1 (0.39) | TTRIL2KLKB1FOLH1OPRK1 | |
| SCHEMBL12342513 | 0.89 | OPRK1 (0.39) | TTRIL2KLKB1FOLH1OPRK1 | |
| SCHEMBL24175888 | 0.88 | TTR (0.40) | TTRIL2FOLH1F2RL1OPRM1 | |
| SCHEMBL24335147 | 0.87 | TTR (0.43) | TTRIL2KLKB1FOLH1PLG | |
| SCHEMBL26412265 | 0.86 | TTR (0.42) | TTRIL2KLKB1FOLH1PLG | |
| SCHEMBL14329043 | 0.86 | CCKBR (0.39) | TTRIL2FOLH1OPRK1F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022678-A1 | ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF | 烟台迈百瑞国际生物医药股份有限公司 | 2021-02-11 | — | — | WO | disclosed |