Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 8/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 6/20 | 0.32 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24543192 | 1.00 | OPRK1 (0.34) | OPRK1JAK3TEAD1TEAD3BTK | |
| SCHEMBL22969807 | 0.85 | JAK3 (0.38) | OPRK1JAK3TEAD1 | |
| SCHEMBL22969802 | 0.81 | JAK3 (0.36) | OPRK1JAK3TEAD1 | |
| SCHEMBL24542941 | 0.81 | JAK3 (0.36) | OPRK1JAK3TEAD1 | |
| SCHEMBL28768719 | 0.78 | OPRK1 (0.39) | OPRK1JAK3TEAD1TEAD3BTK | |
| SCHEMBL28768720 | 0.78 | OPRK1 (0.39) | OPRK1JAK3TEAD1TEAD3BTK | |
| SCHEMBL23545018 | 0.77 | JAK3 (0.40) | OPRK1JAK3TEAD1BTK | |
| SCHEMBL27284053 | 0.77 | JAK3 (0.40) | OPRK1JAK3TEAD1BTK | |
| SCHEMBL20083905 | 0.76 | CHRNB2 (0.43) | — | |
| SCHEMBL24854392 | 0.76 | JAK3 (0.35) | OPRK1JAK3TEAD1TEAD3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023247-A1 | KRAS MUTANT PROTEIN INHIBITOR | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2021-02-11 | — | — | WO | disclosed |