Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 18/20 | 0.69 |
| ▸ | PRKCZ | Q05513 | 17/20 | 0.69 |
| ▸ | PRKD3 | O94806 | 16/20 | 0.69 |
| ▸ | PRKCG | P05129 | 16/20 | 0.69 |
| ▸ | PRKCB | P05771 | 16/20 | 0.69 |
| ▸ | PRKCA | P17252 | 16/20 | 0.69 |
| ▸ | PRKCH | P24723 | 16/20 | 0.69 |
| ▸ | PRKCI | P41743 | 16/20 | 0.69 |
| ▸ | PRKCE | Q02156 | 16/20 | 0.69 |
| ▸ | PRKCD | Q05655 | 16/20 | 0.69 |
| ▸ | PRKD1 | Q15139 | 16/20 | 0.69 |
| ▸ | PRKACA | P17612 | 16/20 | 0.69 |
| ▸ | PRKACB | P22694 | 16/20 | 0.69 |
| ▸ | PRKACG | P22612 | 15/20 | 0.69 |
| ▸ | EGFR | P00533 | 14/20 | 0.69 |
| ▸ | SRC | P12931 | 4/20 | 0.69 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.69 |
| ▸ | JAK2 | O60674 | 2/20 | 0.69 |
| ▸ | ABL1 | P00519 | 2/20 | 0.69 |
| ▸ | LCK | P06239 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24105686 | 1.00 | PRKCQ (0.69) | PRKCQPRKCZPRKD3PRKCGPRKCB | |
| SCHEMBL20048217 | 1.00 | PRKCQ (0.69) | PRKCQPRKCZPRKD3PRKCGPRKCB | |
| SCHEMBL16946994 | 1.00 | PRKCQ (0.69) | PRKCQPRKCZPRKD3PRKCGPRKCB | |
| SCHEMBL20412063 | 1.00 | PRKCQ (0.69) | PRKCQPRKCZPRKD3PRKCGPRKCB | |
| SCHEMBL25474293 | 0.89 | PRKCZ (0.66) | PRKCQPRKCZPRKD3PRKCGPRKCB | |
| SCHEMBL20609293 | 0.84 | PRKCQ (0.65) | PRKCQPRKCZPRKD3PRKCGPRKCB | |
| SCHEMBL12259742 | 0.83 | ALDH1A1 (0.69) | PRKCQPRKCZPRKD3PRKCGPRKCB | |
| Midostaurin SCHEMBL22599853 | 0.81 | PRKCQ (1.00) | PRKCQPRKCZPRKD3PRKCGPRKCB | |
| Midostaurin SCHEMBL20130811 | 0.81 | PRKCQ (1.00) | PRKCQPRKCZPRKD3PRKCGPRKCB | |
| Midostaurin SCHEMBL8486109 | 0.81 | PRKCQ (1.00) | PRKCQPRKCZPRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021024202-A1 | PROCESS FOR THE PREPARATION OF AMORPHOUS MIDOSTAURIN WITH A LOW CONTENT OF RESIDUAL ORGANIC SOLVENT | PROCOS S.P.A. (IT) | 2021-02-11 | — | — | WO | disclosed |