SCHEMBL229721

SCHEMBL229721

C=C(C)C(=O)OC[Si](OC(C)C)(OC(C)C)OC(C)C

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
THRB P10828 1/20 0.40
ALDH1A1 P00352 2/20 0.38
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15861459 0.84 TSHR (0.47) TSHRTHRBALDH1A1
SCHEMBL230324 0.83 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL228106 0.83 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL2241433 0.81 TSHR (0.48) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL29273381 0.79 TSHR (0.39) TSHRALDH1A1TDP1
SCHEMBL16534864 0.79 TSHR (0.55) TSHRTHRBALDH1A1
SCHEMBL133182 0.79 TSHR (0.50) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL396761 0.78 TSHR (0.48) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL82401 0.78 TSHR (0.47) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL28617940 0.78 TSHR (0.49) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021190753-A1 ARTIFICIAL STONE COMPOSITION COMPRISING A SILANE CONDENSATION PRODUCT AS AN ADHESION PROMOTER WACKER CHEMIE AG (DE) 2021-09-30 WO disclosed
WO-2021190751-A1 ARTIFICIAL STONE COMPOSITION COMPRISING ALPHA-SILANE AS AN ADHESION PROMOTER WACKER CHEMIE AG (DE) 2021-09-30 WO disclosed
EP-2941460-B1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF COATINGS GMBH (DE) 2017-11-22 EP disclosed
US-9683125-B2 One-component, curable coating compositions, processes for making and using them, and coatings and articles prepared with them BASF COATINGS GMBH (DE) 2017-06-20 US disclosed
US-20150337159-A1 One-Component, Curable Coating Compositions, Processes For Making And Using Them, And Coatings And Articles Prepared With Them BASF COATINGS GMBH (DE) 2015-11-26 US disclosed
EP-2941460-A1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF Coatings GmbH (DE) 2015-11-11 EP disclosed
US-8865851-B2 Moisture-curing coating compositions comprising aprotic solvents and binders having alkoxysilane groups and method of forming a multicoat finish therewith BASF COATINGS GMBH (DE) 2014-10-21 US disclosed
WO-2014106552-A1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF COATINGS GMBH (DE) 2014-07-10 WO disclosed
EP-2414466-B1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS, COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS, AND THE USE THEREOF BASF COATINGS GMBH (DE) 2013-10-16 EP disclosed
US-8247590-B2 Method for preventing polymerization of unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2012-08-21 US disclosed
US-7619108-B2 Process for preparing unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2009-11-17 US disclosed
EP-1954701-B1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2009-03-18 EP disclosed
WO-2009003804-A1 PRODUCTION OF A COMPOSITE COMPRISING INORGANIC MATERIAL AND ORGANIC POLYMER WACKER CHEMIE AG (DE) 2009-01-08 WO disclosed
US-20080293958-A1 Process for Preparing Unsaturated Organosilicon Compounds WACKER CHEMIE AG (DE) 2008-11-27 US disclosed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
EP-1469002-A1 Method for stabilizing unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2004-10-20 EP disclosed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed
EP-1249454-A1 Preparation of unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2002-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TSHR 4650/4885THRB 4533/4885ALDH1A1 402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.