SCHEMBL228106

SCHEMBL228106

C=C(C)C(=O)OC[Si](C)(C)OC(C)C

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
ALDH1A1 P00352 2/20 0.41
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL230324 0.85 TSHR (0.50) TSHRALDH1A1THRB
SCHEMBL13492055 0.84 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL229721 0.83 TSHR (0.52) TSHRALDH1A1THRB
SCHEMBL7190871 0.80 TSHR (0.47) TSHRALDH1A1THRB
SCHEMBL332509 0.80 TSHR (0.47) TSHRALDH1A1THRB
SCHEMBL229726 0.80 TSHR (0.49) TSHRALDH1A1THRB
SCHEMBL229519 0.79 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL22115832 0.77 TSHR (0.54) TSHRALDH1A1THRB
SCHEMBL9915559 0.77 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL5401378 0.77 TSHR (0.44) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8247590-B2 Method for preventing polymerization of unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2012-08-21 US disclosed
EP-2334690-B1 METHOD FOR PRODUCING (METH)ACRYLOSILANES WACKER CHEMIE AG (DE) 2012-07-25 EP disclosed
EP-2300486-B1 METHOD FOR PREVENTING POLYMERIZATION OF UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2012-03-28 EP disclosed
US-20120004437-A1 METHOD FOR PRODUCING (METH)ACRYLOSILANES WACKER CHEMIE AG (DE) 2012-01-05 US disclosed
EP-2334690-A1 METHOD FOR PRODUCING (METH)ACRYLOSILANES Wacker Chemie AG (DE) 2011-06-22 EP disclosed
US-20110118493-A1 METHOD FOR PREVENTING POLYMERIZATION OF UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2011-05-19 US disclosed
US-7619108-B2 Process for preparing unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2009-11-17 US disclosed
EP-1954701-B1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2009-03-18 EP disclosed
US-20080293958-A1 Process for Preparing Unsaturated Organosilicon Compounds WACKER CHEMIE AG (DE) 2008-11-27 US disclosed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
EP-1469002-A1 Method for stabilizing unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2004-10-20 EP disclosed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed
EP-1249454-A1 Preparation of unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2002-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TSHR 4650/4885ALDH1A1 402/4885THRB 4533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.