Phosphoric Acid

Phosphoric Acid

SCHEMBL22974795

O=P(O)(O)O.O=P(O)(OCCOc1ccccc1)OCCOc1ccccc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KCNA3 known ✓ P22001 1/20 0.50
PKM P14618 2/20 0.65
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
ALDH1A1 P00352 2/20 0.50
TSHR P16473 2/20 0.50
RECQL P46063 1/20 0.50
PARP10 Q53GL7 1/20 0.49
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
THRB P10828 1/20 0.46
HPGD P15428 1/20 0.46
MAPT P10636 1/20 0.46
FDPS P14324 2/20 0.45
TAAR1 Q96RJ0 1/20 0.45
SRC P12931 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1309388 0.98 PKM (0.67) PKMCYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL18141271 0.90 PKM (0.62) PKMCYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL18140739 0.90 PKM (0.62) PKMCYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL28223074 0.89 PKM (0.61) PKMCYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL18141396 0.87 PKM (0.64) PKMCYP2C9CYP2C19ALDH1A1RECQL
SCHEMBL28176043 0.87 PKM (0.59) PKMCYP2C9CYP2C19ALDH1A1RECQL
SCHEMBL13624424 0.87 PKM (0.58) PKMCYP2C9CYP2C19TSHRRECQL
SCHEMBL427191 0.86 PKM (0.67) PKMCYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL18141772 0.85 LTA4H (0.57) PKMTSHRFDPS
SCHEMBL7124847 0.85 PKM (0.65) PKMCYP2C9CYP2C19ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3778772-B1 POLYESTER RESIN COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2023-11-29 EP disclosed
US-20210147619-A1 POLYESTER RESIN COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-05-20 US disclosed
EP-3778772-A1 POLYESTER RESIN COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-02-17 EP disclosed