Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298492 | 0.82 | DPP4 (0.38) | DPP4 | |
| SCHEMBL2298520 | 0.82 | DPP4 (0.35) | DPP4 | |
| SCHEMBL2302363 | 0.79 | DPP4 (0.30) | DPP4 | |
| SCHEMBL2298751 | 0.77 | ATM (0.34) | — | |
| SCHEMBL2296486 | 0.72 | — | — | |
| SCHEMBL2299117 | 0.72 | — | — | |
| SCHEMBL2296528 | 0.69 | SIGMAR1 (0.33) | DPP4 | |
| SCHEMBL9924117 | 0.68 | GAA (0.32) | — | |
| SCHEMBL12724663 | 0.64 | CACNA1H (0.37) | — | |
| SCHEMBL2299639 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7999006-B2 | Anticancer agents; mitogen-activated protein kinases (MEK) | EXELIXIS, INC. (US) | 2011-08-16 | — | — | US | claimed |