Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298492 | 0.81 | DPP4 (0.38) | DPP4 | |
| SCHEMBL2298520 | 0.81 | DPP4 (0.35) | DPP4 | |
| SCHEMBL2297645 | 0.79 | DPP4 (0.41) | DPP4 | |
| SCHEMBL25043343 | 0.78 | KDM4E (0.40) | DPP4 | |
| SCHEMBL2299117 | 0.78 | — | — | |
| SCHEMBL2298751 | 0.75 | ATM (0.34) | — | |
| SCHEMBL2296486 | 0.74 | — | — | |
| SCHEMBL14433561 | 0.72 | NPSR1 (0.39) | — | |
| SCHEMBL2296528 | 0.71 | SIGMAR1 (0.33) | DPP4 | |
| SCHEMBL18159704 | 0.69 | CACNA1H (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7999006-B2 | Anticancer agents; mitogen-activated protein kinases (MEK) | EXELIXIS, INC. (US) | 2011-08-16 | — | — | US | claimed |