Styrene

Styrene

SCHEMBL2297805

C=C(C)C(=O)OC.C=C(CC(CC)CCCC)C(=O)O.C=Cc1ccccc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
CA2 P00918 1/20 0.39
CYP3A4 P08684 1/20 0.39
KDM4E B2RXH2 1/20 0.38
LMNA P02545 3/20 0.37
MAPK1 P28482 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
HDAC3 O15379 4/20 0.36
HDAC4 P56524 3/20 0.36
HDAC1 Q13547 3/20 0.36
HDAC7 Q8WUI4 3/20 0.36
HDAC2 Q92769 3/20 0.36
HDAC10 Q969S8 3/20 0.36
HDAC11 Q96DB2 3/20 0.36
HDAC8 Q9BY41 3/20 0.36
HDAC6 Q9UBN7 3/20 0.36
HDAC9 Q9UKV0 3/20 0.36
HDAC5 Q9UQL6 3/20 0.36
TSHR P16473 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL2045081 0.90 ALDH1A1 (0.43) ALDH1A1CA2CYP3A4KDM4ELMNA
SCHEMBL4797583 0.86 ALDH1A1 (0.43) ALDH1A1CA2CYP3A4MAPK1TSHR
Styrene SCHEMBL28988056 0.86 ALDH1A1 (0.50) ALDH1A1CA2CYP3A4KDM4ELMNA
Styrene SCHEMBL6342794 0.86 ALDH1A1 (0.38) ALDH1A1CA2CYP3A4KDM4ELMNA
Styrene SCHEMBL2820861 0.85 ALDH1A1 (0.40) ALDH1A1CA2CYP3A4KDM4ELMNA
Styrene SCHEMBL1091932 0.85 LMNA (0.41) ALDH1A1CA2CYP3A4KDM4ELMNA
Styrene SCHEMBL2134956 0.84 LMNA (0.39) ALDH1A1KDM4ELMNATAS1R3TAS1R1
Styrene SCHEMBL7760829 0.84 TSHR (0.57) ALDH1A1CA2CYP3A4KDM4ELMNA
Styrene SCHEMBL2352031 0.83 TSHR (0.59) ALDH1A1CA2CYP3A4KDM4ELMNA
Methacrylic Acid SCHEMBL1172436 0.83 ALDH1A1 (0.40) ALDH1A1CA2CYP3A4LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7993732-B2 Heat-sensitive pressure-sensitive adhesive and heat-sensitive adhesive material RICOH COMPANY, LTD. (JP) 2011-08-09 US disclosed
US-20080026205-A1 Heat-sensitive pressure-sensitive adhesive and heat-sensitive adhesive material RICOH COMPANY, LTD. (JP) 2008-01-31 US disclosed