Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RHEB | Q15382 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19013560 | 0.80 | NR1H2 (0.43) | SLC9A1 | |
| SCHEMBL16835425 | 0.73 | OXER1 (0.46) | POLBKMT2A | |
| SCHEMBL25253592 | 0.70 | KMO (0.41) | PLA2G10KDM4EFABP4LMNAMAPT | |
| SCHEMBL19013496 | 0.68 | NR1H2 (0.42) | SLC9A1 | |
| SCHEMBL3922585 | 0.68 | GLO1 (0.40) | MAPTHTTMEN1KMT2ARAB9A | |
| SCHEMBL29631856 | 0.68 | NR1H2 (0.42) | SLC9A1 | |
| SCHEMBL996292 | 0.68 | ABCB1 (0.50) | KDM4EPOLBAGTR1LMNAMAPT | |
| SCHEMBL27343262 | 0.67 | KDM4E (0.54) | PLA2G10KDM4EPOLBFABP4MAPT | |
| SCHEMBL28815311 | 0.67 | KDM4E (0.57) | KDM4ELMNAMEN1KMT2ARAB9A | |
| SCHEMBL2276306 | 0.66 | SLC9A1 (0.64) | PLA2G10SLC9A1F10KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026672-A1 | HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS | NOVARTIS AG (CH) | 2021-02-18 | — | — | WO | disclosed |