Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 8/20 | 0.62 |
| ▸ | NOS3 | P29474 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3307581 | 0.77 | NOS2 (0.53) | NOS2NOS3KDM4EALDH1A1DRD2 | |
| SCHEMBL8057615 | 0.77 | NOS2 (1.00) | NOS2NOS3DRD2DRD3MAP3K14 | |
| SCHEMBL22995934 | 0.74 | NOS2 (0.59) | NOS2NOS3KDM4EALDH1A1CYP1A2 | |
| SCHEMBL22978813 | 0.74 | ALDH1A1 (0.68) | NOS2NOS3KDM4EALDH1A1DRD2 | |
| SCHEMBL30952115 | 0.74 | ALDH1A1 (0.68) | NOS2NOS3KDM4EALDH1A1DRD2 | |
| SCHEMBL3307465 | 0.73 | NOS2 (0.61) | NOS2NOS3KDM4EALDH1A1DRD2 | |
| SCHEMBL1363642 | 0.70 | NOS3 (0.44) | NOS2NOS3KDM4EALDH1A1DRD2 | |
| SCHEMBL20645736 | 0.69 | NOS2 (0.56) | NOS2NOS3DRD2DRD3TAAR1 | |
| SCHEMBL22995932 | 0.68 | KDM4E (0.63) | NOS2NOS3KDM4EALDH1A1CYP1A2 | |
| SCHEMBL30952113 | 0.68 | KDM4E (0.63) | NOS2NOS3KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112789276-B | Analgesic compounds, process for their preparation and their use in medicine | 上海海雁医药科技有限公司 | 2024-07-30 | — | — | CN | disclosed |
| WO-2021027304-A1 | ANALGESIC COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 上海海雁医药科技有限公司 | 2021-02-18 | — | — | WO | disclosed |
| WO-2021027304-A1 | ANALGESIC COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 上海海雁医药科技有限公司 | 2021-02-18 | — | — | WO | disclosed |