Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979824 | 0.93 | MAPT (0.38) | ALDH1A1KDM4EPOLBADORA3MAPT | |
| SCHEMBL29646350 | 0.90 | MMP9 (0.40) | ALDH1A1KDM4EPOLBADORA3MAPT | |
| SCHEMBL22987685 | 0.90 | MMP9 (0.40) | ALDH1A1KDM4EPOLBADORA3MAPT | |
| SCHEMBL22980168 | 0.89 | KDM4E (0.40) | ALDH1A1KDM4EPOLBADORA3MAPT | |
| SCHEMBL22979352 | 0.87 | BRD4 (0.32) | ALDH1A1KDM4EADORA3ADORA2AADORA1 | |
| SCHEMBL22979411 | 0.87 | KDM4E (0.41) | ALDH1A1KDM4EPOLBADORA3MAPT | |
| SCHEMBL22979362 | 0.86 | MAPT (0.38) | ALDH1A1KDM4EPOLBADORA3MAPT | |
| SCHEMBL22979649 | 0.85 | KDM4E (0.41) | ALDH1A1KDM4EPOLBADORA3MAPT | |
| SCHEMBL22979082 | 0.85 | ADORA3 (0.37) | ALDH1A1KDM4EPOLBADORA3MAPT | |
| SCHEMBL22979873 | 0.85 | ADORA3 (0.37) | ALDH1A1KDM4EPOLBADORA3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |