Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.30 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.30 |
| ▸ | RPS17 | P08708 | 1/20 | 0.30 |
| ▸ | RPSA | P08865 | 1/20 | 0.30 |
| ▸ | RPS2 | P15880 | 1/20 | 0.30 |
| ▸ | RPL35A | P18077 | 1/20 | 0.30 |
| ▸ | RPL7 | P18124 | 1/20 | 0.30 |
| ▸ | RPL17 | P18621 | 1/20 | 0.30 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29646359 | 0.90 | JAK2 (0.33) | ADORA3ADORA1ADORA2AIRAK1 | |
| SCHEMBL22987766 | 0.90 | JAK2 (0.33) | ADORA3ADORA1ADORA2AIRAK1 | |
| SCHEMBL22979734 | 0.89 | CREBBP (0.35) | BRD4CREBBPADORA3ADORA1ADORA2A | |
| SCHEMBL22979512 | 0.89 | ADORA3 (0.34) | BRD4CREBBPADORA3ADORA1ADORA2A | |
| SCHEMBL22979062 | 0.87 | CREBBP (0.37) | BRD4CREBBPADORA3ADORA1ADORA2A | |
| SCHEMBL22979308 | 0.87 | ALDH1A1 (0.38) | ADORA3ADORA1ADORA2AKDM4EALDH1A1 | |
| SCHEMBL29646119 | 0.87 | ADORA2A (0.36) | ADORA3ADORA1ADORA2AIRAK1ADORA2B | |
| SCHEMBL22979719 | 0.87 | ADORA2A (0.36) | ADORA3ADORA1ADORA2AIRAK1ADORA2B | |
| SCHEMBL22979177 | 0.86 | CREBBP (0.33) | BRD4CREBBPADORA3ADORA1ADORA2A | |
| SCHEMBL22979421 | 0.85 | ADORA3 (0.33) | ADORA3ADORA1ADORA2AIRAK1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-13 | — | — | US | disclosed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | AHR, HRH4, HRH1 | BRD4 443/4885CREBBP 2500/4885ADORA3 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.