Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 13/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.31 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.31 |
| ▸ | RPS17 | P08708 | 1/20 | 0.31 |
| ▸ | RPSA | P08865 | 1/20 | 0.31 |
| ▸ | RPS2 | P15880 | 1/20 | 0.31 |
| ▸ | RPL35A | P18077 | 1/20 | 0.31 |
| ▸ | RPL7 | P18124 | 1/20 | 0.31 |
| ▸ | RPL17 | P18621 | 1/20 | 0.31 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.31 |
| ▸ | RPS3 | P23396 | 1/20 | 0.31 |
| ▸ | RPS12 | P25398 | 1/20 | 0.31 |
| ▸ | RPL13 | P26373 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979734 | 0.91 | CREBBP (0.35) | ADORA3ADORA2ACREBBPBRD4ADORA1 | |
| SCHEMBL22979749 | 0.90 | ADORA3 (0.32) | ADORA3ADORA2AADORA1ADORA2BAURKA | |
| SCHEMBL29645740 | 0.90 | ADORA3 (0.32) | ADORA3ADORA2AADORA1ADORA2BAURKA | |
| SCHEMBL29649011 | 0.89 | ADORA3 (0.35) | ADORA3ADORA2AADORA1 | |
| SCHEMBL22988240 | 0.89 | ADORA3 (0.35) | ADORA3ADORA2AADORA1 | |
| SCHEMBL28730362 | 0.89 | ADORA3 (0.35) | ADORA3ADORA2AADORA1 | |
| SCHEMBL22979062 | 0.89 | CREBBP (0.37) | ADORA3ADORA2ACREBBPBRD4ADORA1 | |
| SCHEMBL22979352 | 0.89 | BRD4 (0.32) | ADORA3ADORA2ACREBBPBRD4ADORA1 | |
| SCHEMBL22979177 | 0.88 | CREBBP (0.33) | ADORA3ADORA2ACREBBPBRD4ADORA1 | |
| SCHEMBL22988306 | 0.87 | ADORA2A (0.35) | ADORA3ADORA2AADORA1ADORA2BRPLP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |