Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 5/20 | 0.37 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979954 | 0.90 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL22988241 | 0.90 | RET (0.36) | CREBBPBRD4PIK3CDPIK3R1CCNK | |
| SCHEMBL22979512 | 0.89 | ADORA3 (0.34) | CREBBPBRD4ADORA3ADORA2AADORA1 | |
| SCHEMBL22979734 | 0.89 | CREBBP (0.35) | CREBBPBRD4PIK3CDADORA3ADORA2A | |
| SCHEMBL22979015 | 0.88 | UCHL1 (0.33) | PIK3CD | |
| SCHEMBL22979352 | 0.87 | BRD4 (0.32) | CREBBPBRD4ADORA3ADORA2AADORA1 | |
| SCHEMBL22979950 | 0.87 | CREBBP (0.35) | CREBBPBRD4PIK3CDPIK3R1ADORA3 | |
| SCHEMBL22979177 | 0.86 | CREBBP (0.33) | CREBBPBRD4ADORA3ADORA2AADORA1 | |
| SCHEMBL22988494 | 0.85 | CHEK1 (0.34) | CREBBPBRD4PIK3CDPIK3R1ADORA3 | |
| SCHEMBL29645422 | 0.85 | CHEK1 (0.34) | CREBBPBRD4PIK3CDPIK3R1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |