SCHEMBL2297987

SCHEMBL2297987

C=CCSSc1nnc(S)s1

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
TRPA1 O75762 2/20 0.36
CYP3A4 P08684 2/20 0.36
HPGD P15428 2/20 0.36
ALOX15 P16050 1/20 0.36
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL176389 0.86 ALDH1A1 (0.43) ALDH1A1TRPA1CYP3A4HPGDALOX15
SCHEMBL1719700 0.85 MAPT (0.41) ALDH1A1CYP3A4HPGDMAPT
SCHEMBL7576775 0.76 ALDH1A1 (0.34) ALDH1A1TRPA1CYP3A4HPGDALOX15
SCHEMBL918273 0.75 FBP1 (0.48)
SCHEMBL21727304 0.71 FBP1 (0.39)
SCHEMBL2358144 0.69 MAPT (0.46) ALDH1A1CYP3A4HPGDMAPT
SCHEMBL17702568 0.68 GAA (0.40) ALDH1A1HPGDALOX15MAPT
SCHEMBL28411026 0.67
SCHEMBL17153754 0.67 APEX1 (0.42) ALDH1A1
SCHEMBL6123116 0.67 ALDH1A1 (0.45) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0208513-B1 LUBRICATING COMPOSITIONS ETHYL PETROLEUM ADDITIVES, INC. (US) 1989-08-23 EP claimed
US-4639324-A WEAR AND OXIDATION RESISTANCE ADDITIVES ETHYL PETROLEUM ADDITIVES, INC. (US) 1987-01-27 US claimed
EP-0208513-A2 Lubricating compositions ETHYL PETROLEUM ADDITIVES, INC. (US) 1987-01-14 EP claimed
US-4188297-A Lubricant additive EDWIN COOPER AND COMPANY LIMITED (GB) 1980-02-12 US claimed
JP-11279580-A None JP disclosed
EP-4388066-A1 METHOD OF LUBRICATING AN AUTOMOTIVE OR INDUSTRIAL GEAR The Lubrizol Corporation (US) 2024-06-26 EP disclosed
CN-117836395-A Method for lubricating automobile or industrial gears 路博润公司 2024-04-05 CN disclosed
CN-117813366-A Method for lubricating automobile or industrial gears 路博润公司 2024-04-02 CN disclosed
WO-2023022931-A1 METHOD OF LUBRICATING AN AUTOMOTIVE OR INDUSTRIAL GEAR THE LUBRIZOL CORPORATION (US) 2023-02-23 WO disclosed
CN-115003775-A Colorants for heat transfer fluids and compositions containing the same KD精细化工有限公司 2022-09-02 CN disclosed
CN-114574270-A Durable lubricating fluid for electric vehicles 雅富顿化学公司 2022-06-03 CN disclosed
CN-111356754-A Transmission lubricant composition 巴斯夫欧洲公司 2020-06-30 CN disclosed
EP-0395258-A1 Process for preparing sulfurized branched alkyl phosphite lubricant additive ETHYL PETROLEUM ADDITIVES, INC. (US) 1990-10-31 EP disclosed
US-4871465-A MIXTURE OF ORGANOSULFUR COMPOUNDS AND HYDROCARBON-SUBSTITUTED 1,2,4-TRIAZOLES AMOCO CORPORATION (US) 1989-10-03 US disclosed
EP-0208513-B1 LUBRICATING COMPOSITIONS ETHYL PETROLEUM ADDITIVES, INC. (US) 1989-08-23 EP disclosed
EP-0310364-A1 Chlorine-free silver protective lubricant composition (II) AMOCO CORPORATION (US) 1989-04-05 EP disclosed
EP-0208513-A2 Lubricating compositions ETHYL PETROLEUM ADDITIVES, INC. (US) 1987-01-14 EP disclosed
US-4617136-A LUBRICANT ADDITIVES R. T. VANDERBILT COMPANY, INC. (US) 1986-10-14 US disclosed
US-4188297-A Lubricant additive EDWIN COOPER AND COMPANY LIMITED (GB) 1980-02-12 US disclosed
EP-0006587-A1 Sulfonyl ureas, processes for their preparation and pharmaceutical compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-09 EP disclosed