SCHEMBL1719700

SCHEMBL1719700

C=CCSc1nnc(S)s1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.41
ALDH1A1 P00352 5/20 0.38
RAB9A P51151 4/20 0.37
NPC1 O15118 3/20 0.37
HPGD P15428 2/20 0.37
KDM4E B2RXH2 1/20 0.37
TSHR P16473 1/20 0.36
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KMT2A Q03164 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2358144 0.85 MAPT (0.46) MAPTALDH1A1RAB9ANPC1HPGD
SCHEMBL2297987 0.85 ALDH1A1 (0.36) MAPTALDH1A1HPGDCYP3A4
SCHEMBL985460 0.76 APEX1 (0.43) MAPTALDH1A1RAB9ANPC1HPGD
SCHEMBL6530544 0.76 ALDH1A1 (0.57) MAPTALDH1A1TDP1KMT2A
SCHEMBL9281254 0.76 MAPT (0.44) MAPTALDH1A1RAB9ANPC1HPGD
SCHEMBL10980579 0.76 MAPT (0.62) MAPTALDH1A1RAB9ANPC1HPGD
SCHEMBL11330890 0.74 MAPT (0.40) MAPTALDH1A1RAB9ANPC1HPGD
SCHEMBL17153754 0.73 APEX1 (0.42) ALDH1A1RAB9ANPC1KDM4EPOLB
SCHEMBL918273 0.73 FBP1 (0.48)
SCHEMBL12716522 0.72 ALDH1A1 (0.47) ALDH1A1NPC1HPGDTDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0778335-B1 Grease composition with improved antiwear properties CHEVRON ORONITE CO (US) 2002-08-07 EP claimed
US-5641730-A EFFECTIVE STABILIZERS COMPRISING THE MIXTURE OF ALKALI METAL BORATES AND A THIADIAZOLE COMPOUNDS CHEVRON CHEMICAL COMPANY 1997-06-24 US claimed
EP-0778335-A2 Grease composition with improved antiwear properties CHEVRON CHEMICAL COMPANY (US) 1997-06-11 EP claimed
JP-9176670-A None JP disclosed
CN-118165780-A Driveline and transmission fluids for low speed wear and scuffing 雅富顿化学公司 2024-06-11 CN disclosed
CN-118006380-A Corrosion inhibitors and industrial lubricants containing the same 雅富顿化学公司 2024-05-10 CN disclosed
CN-117736785-A Extreme pressure additives with improved copper corrosion 雅富顿化学公司 2024-03-22 CN disclosed
CN-117285973-A Phosphorus antiwear system for improved gear protection 雅富顿化学公司 2023-12-26 CN disclosed
CN-116948729-A Lubricants for electric and hybrid vehicle applications 雅富顿化学公司 2023-10-27 CN disclosed
CN-115052959-B Silicone functionalized viscosity index improver 雅富顿化学公司 2023-10-20 CN disclosed
CN-116891772-A Durable magnet wire and lubricating fluid for electric and hybrid vehicle applications 雅富顿化学公司 2023-10-17 CN disclosed
EP-0681216-A1 Photographic colour developing process Agfa-Gevaert AG (DE) 1995-11-08 EP disclosed
EP-0310364-B1 CHLORINE-FREE SILVER PROTECTIVE LUBRICANT COMPOSITION (II) AMOCO CORPORATION (US) 1992-05-20 EP disclosed
US-4871465-A MIXTURE OF ORGANOSULFUR COMPOUNDS AND HYDROCARBON-SUBSTITUTED 1,2,4-TRIAZOLES AMOCO CORPORATION (US) 1989-10-03 US disclosed
EP-0310364-A1 Chlorine-free silver protective lubricant composition (II) AMOCO CORPORATION (US) 1989-04-05 EP disclosed
US-4585872-A CEPHALOSPORIN ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-04-29 US disclosed
US-4447429-A ANTIBIOTICS, BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-05-08 US disclosed
EP-0007470-B1 CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-10-12 EP disclosed
US-4268509-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-05-19 US disclosed
EP-0007470-A2 Cephem compounds, processes for their preparation and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-02-06 EP disclosed