SCHEMBL22980773

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22074272	0.90	HTR6 (0.60)	HTR6CPT1ACPT2CPT1BPPARG
	SCHEMBL22980669	0.85	HTR6 (0.78)	HTR6CPT1ACPT2CPT1BSLC1A3
	SCHEMBL22990912	0.85	HTR6 (0.51)	HTR6CPT1ACPT2CPT1BSLC1A3
	SCHEMBL28933624	0.84	HTR6 (0.64)	HTR6CPT1ACPT2CPT1BSLC1A3
	SCHEMBL1898211	0.82	HTR6 (0.56)	HTR6SLC1A3SLC1A2SLC1A1PPARG
	SCHEMBL8652798	0.82	CPT1A (0.63)	HTR6CPT1ACPT2CPT1BSLC1A3
	SCHEMBL20742946	0.79	HTR6 (0.60)	HTR6PPARGPPARDPPARAFABP4
	SCHEMBL9372377	0.79	CPT1A (0.54)	HTR6CPT1ACPT2CPT1BSLC1A3
	SCHEMBL30955477	0.79	CPT1A (0.54)	HTR6CPT1ACPT2CPT1BSLC1A3
	SCHEMBL17049351	0.78	PPARG (0.53)	HTR6CPT1ACPT2PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.