Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 6/20 | 0.52 |
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29848557 | 1.00 | MEN1 (0.52) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL3205888 | 0.84 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL31289468 | 0.80 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL986751 | 0.80 | NOTUM (0.45) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL29848847 | 0.80 | NPBWR1 (0.57) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6483416 | 0.80 | ALDH1A1 (0.79) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL31289472 | 0.80 | MEN1 (0.58) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL30533210 | 0.79 | MEN1 (0.73) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL1655753 | 0.79 | MEN1 (0.73) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL2246334 | 0.78 | ALDH1A1 (0.77) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021029665-A1 | NOVEL IMIDAZOLE DERIVATIVE EXPRESSING FLT3 INHIBITORY ACTIVITY, AND USE THEREOF | 한양대학교 에리카산학협력단 | 2021-02-18 | — | — | WO | disclosed |
| WO-2021029665-A1 | NOVEL IMIDAZOLE DERIVATIVE EXPRESSING FLT3 INHIBITORY ACTIVITY, AND USE THEREOF | 한양대학교 에리카산학협력단 | 2021-02-18 | — | — | WO | disclosed |