Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 13/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | MMP9 | P14780 | 2/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3190872 | 0.86 | NPBWR1 (0.65) | NPBWR1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL986164 | 0.82 | NPBWR1 (0.45) | NPBWR1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3193088 | 0.80 | NPBWR1 (0.80) | NPBWR1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5566197 | 0.80 | NPC1 (0.78) | NPBWR1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29848557 | 0.80 | MEN1 (0.52) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL22981809 | 0.80 | MEN1 (0.52) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL3204647 | 0.79 | RAB9A (0.60) | NPBWR1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29848496 | 0.79 | SLC6A9 (0.49) | NPBWR1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29848643 | 0.79 | CCNA2 (0.53) | NPBWR1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3183535 | 0.78 | MAPT (0.66) | NPBWR1MAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12473278-B2 | Imidazole derivative expressing FLT3 inhibitory activity, and use thereof | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) | 2025-11-18 | — | — | US | disclosed |
| US-20220315573-A1 | Novel Imidazole Derivative Expressing FLT3 Inhibitory Activity, and Use Thereof | Industry-University Cooperation Foundation Hangyang University Erica Campus (KR) | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315573-A1 | Novel Imidazole Derivative Expressing FLT3 Inhibitory Activity, and Use Thereof | FLT3, FLI1, MCL1 | NPBWR1 4167/4885MAPT 4590/4885RAB9A 3734/4885 |
| US-12473278-B2 | Imidazole derivative expressing FLT3 inhibitory activity, and use thereof | FLT3, FLI1, MCL1 | NPBWR1 4128/4885MAPT 4520/4885RAB9A 3807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.