Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | PDE6D | O43924 | 3/20 | 1.00 |
| ▸ | ALDH2 | P05091 | 1/20 | 1.00 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 5/20 | 0.82 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | HTT | P42858 | 3/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.74 |
| ▸ | TNF | P01375 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | CNR2 | P34972 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | BRD4 | O60885 | 1/20 | 0.64 |
| ▸ | CFTR | P13569 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412068 | 0.91 | ALDH1A1 (0.82) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL5010971 | 0.91 | ALDH1A1 (1.00) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL29411970 | 0.91 | TP53 (0.89) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL15474496 | 0.89 | ALDH1A1 (0.80) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL9006294 | 0.89 | ALDH1A1 (0.80) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL15568856 | 0.89 | ALDH1A1 (0.80) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| Benzaldehyde SCHEMBL28311657 | 0.89 | ALDH1A1 (0.78) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL15568179 | 0.88 | ALDH1A1 (0.78) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL15569395 | 0.88 | ALDH1A1 (0.78) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL29412044 | 0.88 | TP53 (1.00) | ALDH1A1PDE6DALDH2ALDH3A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014027053-A1 | BENZIMIDAZOLES FOR THE TREATMENT OF CANCER | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-02-20 | — | — | WO | claimed |
| EP-2698367-A1 | Benzimidazoles for the treatment of cancer | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-02-19 | — | — | EP | claimed |
| US-4542394-A | MULTILAYER-DIAZONIUM LAYER AND COUPLER LAYER CONTAINING BENZIMIDAZOLE COMPOUND | RICOH COMPANY, LTD. (JP) | 1985-09-17 | — | — | US | claimed |
| US-12534666-B2 | Blue phosphorescent material, production method thereof, and photophysical properties thereof | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) | 2026-01-27 | — | — | US | disclosed |
| US-20220333007-A1 | Blue Phosphorescent Material, Production Method Thereof, and Photophysical Properties Thereof | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) | 2022-10-20 | — | — | US | disclosed |
| CN-111978301-B | Benzimidazole compound with endothelial lipase inhibition effect and application thereof | 盐城师范学院 | 2022-08-02 | — | — | CN | disclosed |
| WO-2022057930-A1 | BENZIMIDAZOLE COMPOUND HAVING ENDOTHELIAL LIPASE INHIBITION EFFECT, AND APPLICATION | 盐城师范学院 | 2022-03-24 | — | — | WO | disclosed |
| CN-108997221-B | Method for synthesizing 1, 2-disubstituted benzimidazole compound by using 3-hydroxy-2-naphthoic acid and dichlorotitanocene | 陕西师范大学 | 2021-10-01 | — | — | CN | disclosed |
| WO-2021096268-A2 | BLUE PHOSPHORESCENT MATERIAL, PRODUCTION METHOD THEREOF, AND PHOTOPHYSICAL PROPERTIES THEREOF | 고려대학교 산학협력단 | 2021-05-20 | — | — | WO | disclosed |
| CN-107311933-B | Benzimidazole derivative, preparation method and application thereof | 中国人民解放军军事医学科学院毒物药物研究所 | 2020-12-22 | — | — | CN | disclosed |
| US-20200390074-A1 | Non-Mammalian RAS Transgenic Animal Model | TOSK, INC. | 2020-12-17 | — | — | US | disclosed |
| CN-1113236-A | Non-peptidyl tachykinin receptor antagonists | LILLY CO ELI (US) | 1995-12-13 | — | — | CN | disclosed |
| US-5473079-A | Process for preparing 2-arylbenzimidazole-5-sulfonic acids | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-12-05 | — | — | US | disclosed |
| EP-0579827-A1 | METHOD OF PREPARING 2-ARYLBENZIMIDAZOLE 5-SULPHONIC ACIDS | MERCK PATENT GmbH (DE) | 1994-01-26 | — | — | EP | disclosed |
| WO-1993015061-A2 | METHOD OF PREPARING 2-ARYLBENZIMIDAZOLE 5-SULPHONIC ACIDS | MERCK PATENT GMBH (DE) | 1993-08-05 | — | — | WO | disclosed |
| CN-1006386-B | PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER | SHINETSU CHEM IND CO (JP) | 1990-01-10 | — | — | CN | disclosed |
| EP-0172427-B1 | PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER | Shin-Etsu Chemical Co., Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4758639-A | Process for production of vinyl polymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| US-4757124-A | Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |
| CN-85107531-A | Process for producing vinyl chloride polymer | — | 1987-01-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12534666-B2 | Blue phosphorescent material, production method thereof, and photophysical properties thereof | OCIAD1, OCIAD2, OPRD1 | ALDH1A1 1095/4885PDE6D 366/4885ALDH2 1104/4885 |
| US-20220333007-A1 | Blue Phosphorescent Material, Production Method Thereof, and Photophysical Properties Thereof | IK, PAICS, PPIP5K2 | ALDH1A1 3759/4885PDE6D 1173/4885ALDH2 3329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.