Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42656 | 0.81 | ALDH1A1 (0.64) | ALDH1A1TSHRMAPK1CYP1A2MEN1 | |
| SCHEMBL8514613 | 0.80 | HSPA5 (0.41) | ALDH1A1TSHRMAPK1CYP1A2MEN1 | |
| SCHEMBL27647600 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPK1CYP1A2MEN1 | |
| SCHEMBL24114958 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1CYP1A2MEN1 | |
| SCHEMBL2177579 | 0.78 | HSPA5 (0.53) | ALDH1A1TSHRMAPK1CYP1A2MEN1 | |
| Alcohol SCHEMBL9286265 | 0.77 | ALDH1A1 (0.60) | ALDH1A1TSHRMAPK1CYP1A2MEN1 | |
| Boric Acid SCHEMBL28025581 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPK1CYP1A2MEN1 | |
| SCHEMBL18476024 | 0.76 | MAPT (0.47) | ALDH1A1TSHRMAPK1CYP1A2MEN1 | |
| SCHEMBL10822034 | 0.76 | HSPA5 (0.66) | ALDH1A1TSHRMAPK1CYP1A2MEN1 | |
| SCHEMBL8572706 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPK1CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258397-B1 | POLYMER CONJUGATE OF PHYSIOLOGICALLY ACTIVE SUBSTANCE | NIPPON KAYAKU KK (JP) | 2017-10-11 | — | — | EP | disclosed |
| US-8920788-B2 | High-molecular weight conjugate of physiologically active substances | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2014-12-30 | — | — | US | disclosed |
| US-20110201754-A1 | High-Molecular Weight Conjugate Of Physiologically Active Substances | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2258397-A1 | POLYMER CONJUGATE OF PHYSIOLOGICALLY ACTIVE SUBSTANCE | Nippon Kayaku Kabushiki Kaisha (JP) | 2010-12-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201754-A1 | High-Molecular Weight Conjugate Of Physiologically Active Substances | OGFR, ACP1, FCGR2A | ALDH1A1 618/4885TSHR 284/4885MAPK1 3095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.