SCHEMBL2298335

SCHEMBL2298335

FC(F)(F)Oc1ccc(C2CCNCC2)cc1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 8/20 0.61
EPHX1 P07099 1/20 0.50
SLC18A3 Q16572 1/20 0.50
SIGMAR1 Q99720 1/20 0.50
P2RY14 Q15391 1/20 0.47
QDPR P09417 1/20 0.43
SCN10A Q9Y5Y9 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
CTSS P25774 1/20 0.41
CTSK P43235 1/20 0.41
NISCH Q9Y2I1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4893644 0.98 HTR2C (0.62) HTR2CEPHX1SLC18A3SIGMAR1P2RY14
SCHEMBL25307338 0.90 HTR3A (0.54) HTR2CEPHX1SCN10A
Trifluoroacetic Acid SCHEMBL942293 0.89 EPHX1 (0.52) HTR2CEPHX1SLC18A3SIGMAR1P2RY14
SCHEMBL4564168 0.87 L3MBTL1 (0.47) HTR2CEPHX1L3MBTL1NISCH
Tert-Butyl Formate SCHEMBL28752731 0.86 HTR2C (0.47) HTR2CEPHX1SLC18A3SIGMAR1P2RY14
SCHEMBL28247613 0.83 MEN1 (0.48) HTR2CEPHX1SCN10AL3MBTL1
SCHEMBL31476801 0.82 HTR2C (0.51) HTR2CSLC18A3SIGMAR1QDPR
SCHEMBL7724468 0.81 EPHX2 (0.48) EPHX1SCN10AL3MBTL1
SCHEMBL14744263 0.81 SCN10A (0.44) HTR2CEPHX1SCN10AL3MBTL1NISCH
SCHEMBL22944159 0.81 SCN10A (0.61) HTR2CSCN10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116768826-B Rupestonic acid amide derivative containing nitrogen heterocycle, and preparation method and application thereof 中国科学院新疆理化技术研究所 2025-05-27 CN claimed
CN-116768826-A Rupestonic acid amide derivative containing nitrogen heterocycle, and preparation method and application thereof 中国科学院新疆理化技术研究所 2023-09-19 CN claimed
EP-4081509-A1 NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA Zydus Lifesciences Limited (IN) 2022-11-02 EP claimed
EP-4076453-A1 A PHARMACEUTICAL ORAL DOSAGE FORM OF Q203 Qurient Co. Ltd. (KR) 2022-10-26 EP claimed
EP-4003521-A1 DIFFERENT FORMS OF 6-CHLORO-2-ETHYL-N-(4-(4-(4-(TRIFLUOROMETHOXY)PHENYL)PIPERIDINE-1-YL)BENZYL)IMIDAZO[1,2-A]PYRIDINE-3-CARBOXAMIDE Qurient Co. Ltd. (KR) 2022-06-01 EP claimed
CN-105524058-B Pyrazolo [1,5 a] pyridine compounds and their and its application 广州艾格生物科技有限公司 2018-03-27 CN claimed
US-20250353863-A1 TRICYCLIC SPIROLACTAM COMPOUNDS WITH ANTIMYCOBACTERIAL ACTIVITY INST NAT SANTE RECH MED (FR) 2025-11-20 US disclosed
CN-116768826-B Rupestonic acid amide derivative containing nitrogen heterocycle, and preparation method and application thereof 中国科学院新疆理化技术研究所 2025-05-27 CN disclosed
CN-114786670-B Oral pharmaceutical dosage form 奎利恩特有限公司 2024-08-30 CN disclosed
US-11820767-B2 Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection UNIVERSITY OF NOTRE DAME DU LAC (US) 2023-11-21 US disclosed
US-11820767-B2 Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection UNIVERSITY OF NOTRE DAME DU LAC (US) 2023-11-21 US disclosed
US-11820767-B2 Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection UNIVERSITY OF NOTRE DAME DU LAC (US) 2023-11-21 US disclosed
CN-116768826-A Rupestonic acid amide derivative containing nitrogen heterocycle, and preparation method and application thereof 中国科学院新疆理化技术研究所 2023-09-19 CN disclosed
US-5789402-A Compounds having effects on serotonin-related systems ELI LILLY COMPANY (US) 1998-08-04 US disclosed
US-5741789-A HETERO-OXY ALKANAMINES ELI LILLY AND COMPANY (US) 1998-04-21 US disclosed
US-5627196-A ANTIDEPRESSANTS AND ANTISEROTONIN AGENTS ELI LILLY AND COMPANY (US) 1997-05-06 US disclosed
US-5614523-A INDOLYLOXY COMPOUNDS ELI LILLY AND COMPANY (US) 1997-03-25 US disclosed
US-5576321-A ALKOXY-SUBSTITUTED INDOLES ELI LILLY AND COMPANY (US) 1996-11-19 US disclosed
WO-1996022290-A1 COMPOUNDS HAVING EFFECTS ON SEROTONIN-RELATED SYSTEMS ELI LILLY AND COMPANY (US) 1996-07-25 WO disclosed
EP-0722941-A2 Compounds having effects on serotonin-related systems ELI LILLY AND COMPANY (US) 1996-07-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11820767-B2 Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection BET1, BRD4, BRD3 HTR2C 3573/4885EPHX1 1198/4885SLC18A3 3789/4885
US-20250353863-A1 TRICYCLIC SPIROLACTAM COMPOUNDS WITH ANTIMYCOBACTERIAL ACTIVITY TALDO1, TBCA, TBCD HTR2C 4064/4885EPHX1 4012/4885SLC18A3 3842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.