SCHEMBL25307338

SCHEMBL25307338

FC(F)(F)Oc1ccc(C2CCNC2)cc1

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 1/20 0.54
SCN10A Q9Y5Y9 1/20 0.52
HTR2C P28335 3/20 0.49
EPHX1 P07099 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22944159 0.92 SCN10A (0.61) HTR3ASCN10AHTR2C
Trifluoroacetic Acid SCHEMBL21381947 0.90 HTR2C (0.50) HTR3ASCN10AHTR2CEPHX1
SCHEMBL2298335 0.90 HTR2C (0.61) SCN10AHTR2CEPHX1
Hydrochloric Acid SCHEMBL4893644 0.88 HTR2C (0.62) SCN10AHTR2CEPHX1
SCHEMBL14744263 0.86 SCN10A (0.44) SCN10AHTR2CEPHX1
SCHEMBL1546444 0.83 DRD2 (0.60)
SCHEMBL1546446 0.83 DRD2 (0.60)
SCHEMBL25240758 0.81 HTR2C (0.54) SCN10AHTR2C
SCHEMBL28247613 0.80 MEN1 (0.48) SCN10AHTR2CEPHX1
Trifluoroacetic Acid SCHEMBL942293 0.80 EPHX1 (0.52) HTR2CEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227428-A1 AMIDO COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227428-A1 AMIDO COMPOUNDS RIPK1, RIPK3, MLKL HTR3A 3838/4885SCN10A 1485/4885HTR2C 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.